Treatment for glioblastoma (GBM)
Intended for US audiences only.
Optune® Novocure™

First glance at Optune®

When you or your loved one receives a GBM diagnosis, you may feel overwhelmed with information. In addition to what your healthcare team may have shared, you may be doing research yourself, and friends and family may send you things they've read.

It may be a lot to take in. But when you're ready, it's important to get organized and take the time to talk to your doctor and learn as much as you can about what treatments may work for you, including Optune.

Here are some topics that other GBM patients and their caregivers found important when learning more about Optune.

1. How would Optune fit into my treatment plan?

If you have newly diagnosed GBM and you and your doctor decide to start Optune, it would be used together with the chemotherapy temozolomide (TMZ), after you have already had surgery and radiation with TMZ.

If you have recurrent GBM and you and your doctor decide to start Optune, Optune would be used alone once treatment options like surgery and radiation have been exhausted.

2. How would I get Optune?

After talking through your treatment plan, your doctor may prescribe Optune.

It's important to note that your doctor must be certified to prescribe Optune. If your doctor is not certified, he or she may refer you to another doctor who is certified. There are certified treatment centers across the United States. You can visit Find a Treatment Center to locate one near you.

As soon as you are ready to start Optune, Novocure will connect with you to discuss insurance coverage and financial assistance, and schedule in-person device training.

3. What kind of support does Novocure offer?

nCompass™ connects patients and their caregivers with a dedicated nCompass Device Support Specialist (DSS) and access to 24/7 technical support. Your DSS will be there to provide device education, help you set up the device for the first time, answer questions, and provide information as to how you may be able to incorporate Optune into your life.

Learn more about patient and caregiver support here.

4. How will Optune fit into my daily life?

Continuous treatment with Optune can be received almost anywhere. You may be able to use Optune while you go about your daily routine at work, for some travel, and at social functions like family get-togethers. No matter where you are, it’s important that you keep the device and arrays from getting wet.

In order for Optune to work properly, you will need to keep your head shaved while using the device. However, loose-knit wigs, hats, and head coverings can all be worn over the arrays.

1. Optune Instructions For Use. Novocure 2016.

Find a certified prescriber

Locate a nearby treatment center where doctors are certified to prescribe Optune.

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Hear Marcia's Perspective

Watch Marcia as she shares her journey with Optune.

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Find a Treatment Center



Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).

Optune with temozolomide is indicated for the treatment of adult patients with newly diagnosed, supratentorial glioblastoma following maximal debulking surgery and completion of radiation therapy together with concomitant standard of care chemotherapy.

For the treatment of recurrent GBM, Optune is indicated following histologically-or radiologically-confirmed recurrence in the supratentorial region of the brain after receiving chemotherapy. The device is intended to be used as a monotherapy, and is intended as an alternative to standard medical therapy for GBM after surgical and radiation options have been exhausted.

Important Safety Information


Do not use Optune if you have an active implanted medical device, a skull defect (such as, missing bone with no replacement), or bullet fragments. Use of Optune together with implanted electronic devices has not been tested and may theoretically lead to malfunctioning of the implanted device. Use of Optune together with skull defects or bullet fragments has not been tested and may possibly lead to tissue damage or render Optune ineffective.

Do not use Optune if you are known to be sensitive to conductive hydrogels. In this case, skin contact with the gel used with Optune may commonly cause increased redness and itching, and rarely may even lead to severe allergic reactions such as shock and respiratory failure.

Warnings and Precautions

Use Optune only after receiving training from qualified personnel, such as your doctor, a nurse, or other medical personnel who have completed a training course given by Novocure (the device manufacturer).

Do not use Optune if you are pregnant, you think you might be pregnant or are trying to get pregnant. It is not known if Optune is safe or effective in these populations.

The most common (≥10%) adverse events involving Optune in combination with temozolomide were low blood platelet count, nausea, constipation, vomiting, fatigue, scalp irritation from device use, headache, convulsions, and depression.

The most common (≥10%) adverse events seen when using Optune alone were scalp irritation from device use and headache.

The following adverse reactions were considered related to Optune when using the device alone: scalp irritation from device use, headache, malaise, muscle twitching, fall and skin ulcer.

All servicing procedures must be performed by qualified and trained personnel.

Do not use any parts that do not come with the Optune Treatment Kit, or that were not sent to you by the device manufacturer or given to you by your doctor.

Do not wet the device or transducer arrays.

If you have an underlying serious skin condition on the scalp, discuss with your doctor whether this may prevent or temporarily interfere with Optune treatment.

Please click here to see the Optune Instructions For Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

Patient Journey videos on this site depict actual patients and caregivers. All other depictions of patients, caregivers, and healthcare professionals are actor portrayals.

Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).