Treatment for glioblastoma (GBM)
Intended for US audiences only.
Optune® Novocure™

How Optune® works

You might be wondering how a device that creates wave-like electric fields can help treat GBM. Here's a look at the science behind Optune.

How does Optune work?

  • GBM cancer cells divide quickly, creating more and more cancerous cells that form a mass, or tumor

  • When Optune is turned on, it creates low-intensity, wave-like electric fields called Tumor Treating Fields, or TTFields. These TTFields are delivered by transducer arrays to the location of a GBM tumor
  • TTFields interfere with GBM cancer cell division. This action slows or stops GBM cancer cells from dividing, and may destroy them

How does Optune treat where the GBM tumor is located?

  • Optune has been shown in clinical studies to safely deliver TTFields to the location of a GBM tumor
  • Optune uses 4 adhesive patches, called tranducer arrays, to deliver TTFields to the location of a GBM tumor. These transducer arrays are applied to your scalp and are connected to the device and battery

Optune® delivers TTFields to the location of a GBM tumor

Optune delivers TTFields to the location of your GBM tumor and has not been shown to affect cells in other parts of the body.

Drugs, like chemotherapy, travel through the bloodstream, affecting cells all over the body

Drugs, like chemotherapy, travel through the bloodstream, affecting cells all over the body.

Learn how Tumor Treating Fields work

Watch how Optune stops cancer cells from dividing

1. Optune Instructions For Use. Novocure 2016.
2. National Institutes of Health. National Cancer Institute. What is cancer? Updated February 9, 2015. Accessed February 8, 2018.
3. Optune Patient Information and Operation Manual. Novocure 2017.
4. Kirson ED, Dbalý V, Tovarys F, et al. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors. Proc Natl Acad Sci U S A. 2007;104(24):10152-10157.
5. MedlinePlus. Chemotherapy. Updated December 21, 2017. Accessed February 8, 2018.

Explore the system

Get to know the device and its components.

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Locate a nearby treatment center where doctors are certified to prescribe Optune.

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What is Optune® approved to treat?

Optune is a wearable, portable, FDA-approved device indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

Recurrent GBM

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

Who should not use Optune?

Optune is not for everyone. Talk to your doctor if you have:

Do not use Optune if you are pregnant or are planning to become pregnant. It is not known if Optune is safe or effective during pregnancy.

What should I know before using Optune?

Optune should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure™, the maker of Optune.

What are the possible side effects of Optune?

Most common side effects of Optune when used together with chemotherapy (temozolomide, or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

The most common side effects when using Optune alone were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

Talk to your doctor if you have any of these side effects or questions.

Please click here to see the Optune Instructions For Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

On this site, patient and healthcare professional videos as well as all images labeled as Optune users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals. All other depictions of patients and caregivers are actor portrayals.

Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).