Treatment for glioblastoma (GBM)
Intended for US audiences only.
Optune® Novocure™

Explore the system

The Second Generation Optune System
Smaller. Lighter. Designed for everyday life.

Novocure™ is pleased to introduce the second generation Optune System. It is smaller and lighter, weighing just 2.7 lbs.

Optune® Components

Optune components

The complete system includes a portable electric field generator, transducer arrays, rechargeable batteries, and more.
Optune® Electric Field Generator

Electric field generator

The portable field generator can be carried with you to generate Tumor Treating Fields (TTFields) as you go about your day.
Optune® Transducer Array

Transducer array

Sterile, single-use transducer arrays are connected to the electric field generator to deliver therapy. Transducer arrays are generally changed at least 2 times per week (every 4 days at most).
Optune® Connection Cable

Connection cable and box

Black and white coded sockets on the cable box help ensure that transducer arrays are properly connected.

Easy access sleeve bag

Openings conveniently located at the top and bottom make it easy to reach device controls

Convertible, 5-in-1 bag

This bag can be worn 5 different ways and has additional battery storage, making it ideal for on-the-go use.

The second generation Optune System offers features that enhance carrying comfort and usability:

  • Easy-grip texture allows for better handling

  • Battery indicator displays power and alerts you when it’s time to change the battery

  • Light-detecting sensor auto-dims the device and the charger in the dark

Other components include:

  • Portable batteries: 4 batteries are provided with each kit; each battery lasts for 2 to 3 hours

  • Charger for portable batteries: Batteries will need to be recharged for 2 to 4 hours. The batteries can be charged and used many times for about 6 to 9 months

  • Plug-in power supply and power cords: New “No-Stop Swap” enables you to swap batteries or power source without disrupting delivery of TTFields

1. Optune Patient Information and Operation Manual. Novocure 2016.

Find a certified prescriber

Locate a nearby treatment center where doctors are certified to prescribe Optune.

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Complete support

Learn how nCompass supports Optune users every step of the way.

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Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).

Optune with temozolomide is indicated for the treatment of adult patients with newly diagnosed, supratentorial glioblastoma following maximal debulking surgery and completion of radiation therapy together with concomitant standard of care chemotherapy.

For the treatment of recurrent GBM, Optune is indicated following histologically-or radiologically-confirmed recurrence in the supratentorial region of the brain after receiving chemotherapy. The device is intended to be used as a monotherapy, and is intended as an alternative to standard medical therapy for GBM after surgical and radiation options have been exhausted.

Important Safety Information


Do not use Optune if you have an active implanted medical device, a skull defect (such as, missing bone with no replacement), or bullet fragments. Use of Optune together with implanted electronic devices has not been tested and may theoretically lead to malfunctioning of the implanted device. Use of Optune together with skull defects or bullet fragments has not been tested and may possibly lead to tissue damage or render Optune ineffective.

Do not use Optune if you are known to be sensitive to conductive hydrogels. In this case, skin contact with the gel used with Optune may commonly cause increased redness and itching, and rarely may even lead to severe allergic reactions such as shock and respiratory failure.

Warnings and Precautions

Use Optune only after receiving training from qualified personnel, such as your doctor, a nurse, or other medical personnel who have completed a training course given by Novocure (the device manufacturer).

Do not use Optune if you are pregnant, you think you might be pregnant or are trying to get pregnant. It is not known if Optune is safe or effective in these populations.

The most common (≥10%) adverse events involving Optune in combination with temozolomide were low blood platelet count, nausea, constipation, vomiting, fatigue, scalp irritation from device use, headache, convulsions, and depression.

The most common (≥10%) adverse events seen when using Optune alone were scalp irritation from device use and headache.

The following adverse reactions were considered related to Optune when using the device alone: scalp irritation from device use, headache, malaise, muscle twitching, fall and skin ulcer.

All servicing procedures must be performed by qualified and trained personnel.

Do not use any parts that do not come with the Optune Treatment Kit, or that were not sent to you by the device manufacturer or given to you by your doctor.

Do not wet the device or transducer arrays.

If you have an underlying serious skin condition on the scalp, discuss with your doctor whether this may prevent or temporarily interfere with Optune treatment.

Please click here to see the Optune Instructions For Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

Patient Journey videos on this site depict actual patients and caregivers. All other depictions of patients, caregivers, and healthcare professionals are actor portrayals.

Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).