Treatment for glioblastoma (GBM)
Intended for US audiences only.

"My transition to Optune® was assisted by the nCompass team who were there from day one."
— JB, an Optune user

Learn more about him
nCompass™ logo

Complete support every step of the way

From your first question about Optune® and throughout your treatment, the nCompass team at Novocure provides customized support based on your needs.

We’re committed to providing answers and resources to help you meet your treatment goals.*

Listening and supporting you from the beginning

Understanding Optune

Understanding Optune

  • Provide information on Optune and how it works
  • Answer questions about the potential benefits and side effects of Optune
Affording Optune

Affording Optune

  • Work with your insurance plan and identify resources to minimize your
    cost for Optune, regardless of your financial situation
Starting Optune

Starting Optune

  • Deliver Optune in-person and provide training to you and your caregivers
    to help you get started
  • Share tips and resources on how to incorporate Optune into your daily life
Moving forward with Optune

Moving forward with Optune

  • Troubleshoot any technical issues 24/7 via phone
  • Reorder supplies, such as transducer arrays or extra batteries
  • Answer ongoing questions about Optune
  • Offer travel tips and resources

"Everyone I spoke to [at nCompass] was kind, patient, and compassionate. They became my best friends, partly because I called them so often, especially in the beginning!"
— Pat, an Optune user

For questions about Optune or services available to you, contact nCompass via phone or email.

24 hour resources

Call us toll free:
1-855-281-9301 (toll free)

Contacting Optune

Or email us:
support@novocure.com

Translation is available in over 240 languages.

*nCompass cannot provide you with medical advice. Consult with your doctor for medical related questions.

International travel support from nCompass is dependent on Optune’s approval status in the destination country.

Next: FAQs >

OPT-1605.5

What is Optune approved to treat?

Optune is indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

Recurrent GBM

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

What is the NovoTTF-100L System approved to treat?

The NovoTTF-100L System is a wearable, portable, FDA-approved device indicated for the treatment of adult patients, with unresectable, locally advanced or metastatic, malignant pleural mesothelioma (MPM) to be used together with standard chemotherapy (pemetrexed and platinum-based chemotherapy).

Who should not use Optune for GBM or the NovoTTF-100L System for MPM?

Optune for GBM and the NovoTTF-100L System for MPM are not for everyone. Talk to your doctor if you have:

Do not use Optune for GBM or the NovoTTF-100L System for MPM if you are pregnant or are planning to become pregnant. It is not known if Optune/the NovoTTF-100L System is safe or effective during pregnancy.

What should I know before using Optune for GBM or the NovoTTF-100L System for MPM?

Optune and the NovoTTF-100L System should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune and the NovoTTF-100L System.

What are the possible side effects of Optune for GBM and the NovoTTF-100L System for MPM?

The most common side effects of Optune when used together with chemotherapy for GBM (temozolomide or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

The most common side effects when using Optune alone for GBM were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

The most common side effects of the NovoTTF-100L System when used together with chemotherapy for MPM (pemetrexed and platinum-based chemotherapy) were low blood platelet count, constipation, nausea, tiredness, chest pain, fatigue, skin irritation from device use, itchy skin, and cough.

Other potential adverse effects associated with the use of the NovoTTF-100L System include: treatment related skin irritation, allergic reaction to the plaster or to the gel, electrode overheating leading to pain and/or local skin burns, infections at sites of electrode contact with the skin, local warmth and tingling sensation beneath the electrodes, muscle twitching, medical site reaction and skin breakdown/skin ulcer.

Talk to your doctor if you have any of these side effects or questions.

Caution: Federal law restricts the NovoTTF-100L System to sale by or on the order of a physician. Humanitarian Device. Authorized by Federal Law for use in the treatment of adult patients with unresectable, locally advanced or metastatic, malignant pleural mesothelioma concurrently with pemetrexed and platinum-based chemotherapy. The effectiveness of this device for this use has not been demonstrated.


Please click here to see the Optune Instructions for Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

Please click here to see the NovoTTF-100L IFU for complete information regarding the device's indications, contraindications, warnings, and precautions.


On this site, patient and healthcare professional videos as well as all images labeled as Optune users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals. All other depictions of patients and caregivers are actor portrayals. Patient images reflect the health status of the patients at the time each photo was taken.

What is Optune approved to treat?

Optune is indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.