Treatment for glioblastoma (GBM)
Intended for US audiences only.

“Even though it's been difficult for me at times, this independent woman has learned to step back and let others help. It’s not a sign of weakness but of strength. Because when you’re fighting a disease like GBM, you need as much help as you can get.” — Pat, an Optune® user

Learn more about Pat

Advocacy groups are here to provide support when you need it.

National advocacy organizations

Tap into the latest information and research by health organizations specializing in the treatment of brain tumors.

American Brain Tumor Association Learn more about brain tumors and treatments, locate support groups and educational meetings nationwide, find brain tumor physicians near you, explore research being conducted and how you can participate in a clinical trial, and read about ways to get involved.

National Brain Tumor Society Funding for brain tumor research, read the latest progress, help give the brain tumor community a voice, and obtain guidance and coaching on how to navigate a brain tumor diagnosis and experience. Check the calendar for upcoming Brain Tumor Walks, Rides, Runs, and "brain freezes."

Head for the Cure Foundation Head for the Cure raises funds, awareness and hope for the brain tumor community by supporting clinical trials and programs, including Brains for the Cure, a patient/caregiver portal providing resources to navigate through the stages of a brain tumor diagnosis.

The Musella Foundation for Brain Tumor Research & Information The Musella Foundation for Brain Tumor Research and Information hosts this site to compile data and organize the brain tumor community. Download a guide for the newly diagnosed and explore financial resources.

EndBrainCancer Initiative/Chris Elliott Fund EndBrainCancer.org EndBrainCancer Initiative/Chris Elliott Fund “Directly Connects” patients and provides immediate access to advanced treatment options, clinical trials and healthcare specialists. Their programs also provide Education/Awareness/Outreach to the brain tumor community and the general public about brain cancer and provides the patient voice in clinical trial design and advocates national public health policy to improve patient outcomes.

Local advocacy organizations

Seek out local support groups that can provide positive support in your area.

Local Support Group Finder Find support groups by state, compliments of the American Brain Tumor Association.

CancerCare® Support Groups Browse online and telephone support groups, plus face-to-face sessions for New York, Connecticut, and New Jersey.

Events throughout the year help you stay inspired and informed.

Events throughout the year to help you stay inspired and informed

August 25, 2019

Optune Open House

OptuneOpenHouse.com

Columbia, MO

12:00 PM CST

To RSVP, call 1-855-281-9301

August 29, 2019

Optune Open House Webinar

OptuneOpenHouse.com

7:00 PM EST

To RSVP, call 1-844-247-1636

September 07, 2019

Optune Open House

OptuneOpenHouse.com

San Jose, CA

11:30 AM PST

To RSVP, call 1-855-281-9301

September 11, 2019

Optune Open House

OptuneOpenHouse.com

Falls Church , VA

6:30 PM EST

To RSVP, call 1-855-281-9301

September 21, 2019

Optune Open House

OptuneOpenHouse.com

Oak Brook, IL

11:00 AM CST

To RSVP, call 1-855-281-9301

September 26, 2019

Optune Open House

OptuneOpenHouse.com

Raleigh, NC

6:00 PM EST

To RSVP, call 1-855-281-9301

September 26, 2019

Optune Open House Webinar

OptuneOpenHouse.com

7:00 PM EST

To RSVP, call 1-844-247-1636

October 01, 2019

Optune Open House

OptuneOpenHouse.com

Columbia, SC

6:00 PM EST

To RSVP, call 1-855-281-9301

October 05, 2019

Optune Open House

OptuneOpenHouse.com

Springfield, IL

11:00 AM CST

To RSVP, call 1-855-281-9301

October 17, 2019

Optune Open House

OptuneOpenHouse.com

Indianapolis, IN

6:00 PM EST

To RSVP, call 1-855-281-9301

October 19, 2019

Optune Open House

OptuneOpenHouse.com

Brookfield, WI

11:30 AM CST

To RSVP, call 1-855-281-9301

October 23, 2019

Optune Open House

OptuneOpenHouse.com

Charleston, SC

6:00 PM EST

To RSVP call 855-281-9301

October 26, 2019

Optune Open House

OptuneOpenHouse.com

Livonia, MI

11:00 AM EST

To RSVP, call 1-855-281-9301

Click here to register for an Optune Open House

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What is Optune approved to treat?

Optune is indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

Recurrent GBM

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

What is the NovoTTF-100L System approved to treat?

The NovoTTF-100L System is a wearable, portable, FDA-approved device indicated for the treatment of adult patients, with unresectable, locally advanced or metastatic, malignant pleural mesothelioma (MPM) to be used together with standard chemotherapy (pemetrexed and platinum-based chemotherapy).

Who should not use Optune for GBM or the NovoTTF-100L System for MPM?

Optune for GBM and the NovoTTF-100L System for MPM are not for everyone. Talk to your doctor if you have:

Do not use Optune for GBM or the NovoTTF-100L System for MPM if you are pregnant or are planning to become pregnant. It is not known if Optune/the NovoTTF-100L System is safe or effective during pregnancy.

What should I know before using Optune for GBM or the NovoTTF-100L System for MPM?

Optune and the NovoTTF-100L System should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune and the NovoTTF-100L System.

What are the possible side effects of Optune for GBM and the NovoTTF-100L System for MPM?

The most common side effects of Optune when used together with chemotherapy for GBM (temozolomide or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

The most common side effects when using Optune alone for GBM were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

The most common side effects of the NovoTTF-100L System when used together with chemotherapy for MPM (pemetrexed and platinum-based chemotherapy) were low blood platelet count, constipation, nausea, tiredness, chest pain, fatigue, skin irritation from device use, itchy skin, and cough.

Other potential adverse effects associated with the use of the NovoTTF-100L System include: treatment related skin irritation, allergic reaction to the plaster or to the gel, electrode overheating leading to pain and/or local skin burns, infections at sites of electrode contact with the skin, local warmth and tingling sensation beneath the electrodes, muscle twitching, medical site reaction and skin breakdown/skin ulcer.

Talk to your doctor if you have any of these side effects or questions.


Please click here to see the Optune Instructions for Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

Please click here to see the NovoTTF-100L IFU for complete information regarding the device's indications, contraindications, warnings, and precautions.

Caution: Federal law restricts the NovoTTF-100L System to sale by or on the order of a physician. Humanitarian Device. Authorized by Federal Law for use in the treatment of adult patients with unresectable, locally advanced or metastatic, malignant pleural mesothelioma concurrently with pemetrexed and platinum-based chemotherapy. The effectiveness of this device for this use has not been demonstrated.


On this site, patient and healthcare professional videos as well as all images labeled as Optune users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals. All other depictions of patients and caregivers are actor portrayals. Patient images reflect the health status of the patients at the time each photo was taken.

What is Optune approved to treat?

Optune is indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.