Treatment for glioblastoma (GBM)
Intended for US audiences only.
Optune® Novocure™
Getting ready for Glioblastoma (GBM) treatment

Preparing for Optune®

You may have already spoken to doctors and done your own research, but as you or your loved one prepares to start treatment with Optune, you might be wondering what more you should know. Here are some things to keep in mind as you get started.

A Device Support Specialist (DSS) will help you get started with Optune

When you're ready to start treatment, nCompass will arrange for in-person training. At that appointment, an nCompass DSS will teach you and your caregivers how to use the device and how to properly place transducer arrays.

Invite caregivers to your treatment education meeting

Many patients rely on family, friends, and/or outside caretakers to assist them on array change days. It’s a good idea to have anyone who will be helping you with array changes present at your treatment education meeting. That way, your caregivers will be able to meet your DSS and learn about the device and proper array placement.

It’s important to keep your head shaved while using Optune

Transducer arrays need to be applied directly to your scalp to work properly. Hair growth prevents the arrays from making good contact with your scalp.

You can cover transducer arrays with breathable head coverings

If you’d like, you can wear a loose-knit wig, hat, or breathable head covering over the transducer arrays.

Your arrays will need to be changed regularly

Transducer arrays need to be changed at least 2 times per week (every 4 days at most). If you find that you sweat a lot or that your hair grows quickly, you may need to change them more often. Watch this tutorial to learn how transducer arrays are applied.

You can wear Optune day and night

Optune should be used for at least 18 hours a day to get the best response from treatment. Therapy can be delivered while you sleep.

Your time on treatment is important

Optune records how much time per day therapy is being delivered. A monthly compliance report is provided to your doctors, so they can discuss your treatment goals with you.

You’ll want to protect Optune from getting wet

It’s important that you keep the device and arrays from getting wet. Your DSS will provide direction on how to protect the transducer arrays and device before bathing. You can learn more about what to do if Optune gets wet on our FAQ page.

Daily life with Optune

You may be able to use Optune while you go about your daily routine at work, for some travel, and at social functions like family get-togethers. You will want to speak with your doctor about whether it is okay for you to continue working or to travel. nCompass can work with you to provide additional batteries or other accommodations to use Optune at your office or while traveling. See how other patients have incorporated Optune into their lives here.

1. Optune Patient Information and Operation Manual. Novocure 2016. 2. Optune Instructions For Use. Novocure 2016.

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Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).

Optune with temozolomide is indicated for the treatment of adult patients with newly diagnosed, supratentorial glioblastoma following maximal debulking surgery and completion of radiation therapy together with concomitant standard of care chemotherapy.

For the treatment of recurrent GBM, Optune is indicated following histologically-or radiologically-confirmed recurrence in the supratentorial region of the brain after receiving chemotherapy. The device is intended to be used as a monotherapy, and is intended as an alternative to standard medical therapy for GBM after surgical and radiation options have been exhausted.

Important Safety Information


Do not use Optune if you have an active implanted medical device, a skull defect (such as, missing bone with no replacement), or bullet fragments. Use of Optune together with implanted electronic devices has not been tested and may theoretically lead to malfunctioning of the implanted device. Use of Optune together with skull defects or bullet fragments has not been tested and may possibly lead to tissue damage or render Optune ineffective.

Do not use Optune if you are known to be sensitive to conductive hydrogels. In this case, skin contact with the gel used with Optune may commonly cause increased redness and itching, and rarely may even lead to severe allergic reactions such as shock and respiratory failure.

Warnings and Precautions

Use Optune only after receiving training from qualified personnel, such as your doctor, a nurse, or other medical personnel who have completed a training course given by Novocure (the device manufacturer).

Do not use Optune if you are pregnant, you think you might be pregnant or are trying to get pregnant. It is not known if Optune is safe or effective in these populations.

The most common (≥10%) adverse events involving Optune in combination with temozolomide were low blood platelet count, nausea, constipation, vomiting, fatigue, scalp irritation from device use, headache, convulsions, and depression.

The most common (≥10%) adverse events seen when using Optune alone were scalp irritation from device use and headache.

The following adverse reactions were considered related to Optune when using the device alone: scalp irritation from device use, headache, malaise, muscle twitching, fall and skin ulcer.

All servicing procedures must be performed by qualified and trained personnel.

Do not use any parts that do not come with the Optune Treatment Kit, or that were not sent to you by the device manufacturer or given to you by your doctor.

Do not wet the device or transducer arrays.

If you have an underlying serious skin condition on the scalp, discuss with your doctor whether this may prevent or temporarily interfere with Optune treatment.

Please click here to see the Optune Instructions For Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

Patient Journey videos on this site depict actual patients and caregivers. All other depictions of patients, caregivers, and healthcare professionals are actor portrayals.

Indications For Use

Optune is intended as a treatment for adult patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).