Treatment for glioblastoma (GBM)
Intended for US audiences only.

Meet Karla

×

Karla:
My name is Karla Harris. I'm coming to you to talk to you about my best friend, Optune.

So I had my head shaved yesterday. I'm a little nervous but very excited to be participating in a program that's going to help not only me, but other people in the future.

Nancy:
My responsibility in all of this is essentially we're going to walk through everything piece-by-piece and get you all really comfortable with the equipment and the device. When you are ready, I'm going to have you initiate treatment. So do you see your blue TTfields? You are officially on Optune.

Karla:
Hey everybody. It's day two of the Optune. I was so worried at first and kind of scared I suppose when they put them on about how hard it might be and how difficult of a challenge it would be. But it's not a problem at all, and today, I have some new hats to try on to wear over my Optune when I go out. And I did go out with a scarf on over the Optune today and no one really looked at me funny or pointed fingers or laughed at me. It went quite well.

I just want to let you all know how important this is today. Because today, at the doctor, we found out this is the only active treatment I can use at this point against the brain cancer. It's been a great experience. I've been able to lead my normal everyday life—all my community meetings and activities. Thank you very much.

Find an Optune doctor

By ZIP code

Join the Facebook group

Connect

What is Optune approved to treat?

Optune is indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

Recurrent GBM

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

What is the NovoTTF-100L System approved to treat?

The NovoTTF-100L System is a wearable, portable, FDA-approved device indicated for the treatment of adult patients, with unresectable, locally advanced or metastatic, malignant pleural mesothelioma (MPM) to be used together with standard chemotherapy (pemetrexed and platinum-based chemotherapy).

Who should not use Optune for GBM or the NovoTTF-100L System for MPM?

Optune for GBM and the NovoTTF-100L System for MPM are not for everyone. Talk to your doctor if you have:

Do not use Optune for GBM or the NovoTTF-100L System for MPM if you are pregnant or are planning to become pregnant. It is not known if Optune/the NovoTTF-100L System is safe or effective during pregnancy.

What should I know before using Optune for GBM or the NovoTTF-100L System for MPM?

Optune and the NovoTTF-100L System should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure®, the maker of Optune and the NovoTTF-100L System.

What are the possible side effects of Optune for GBM and the NovoTTF-100L System for MPM?

The most common side effects of Optune when used together with chemotherapy for GBM (temozolomide or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

The most common side effects when using Optune alone for GBM were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

The most common side effects of the NovoTTF-100L System when used together with chemotherapy for MPM (pemetrexed and platinum-based chemotherapy) were low blood platelet count, constipation, nausea, tiredness, chest pain, fatigue, skin irritation from device use, itchy skin, and cough.

Other potential adverse effects associated with the use of the NovoTTF-100L System include: treatment related skin irritation, allergic reaction to the plaster or to the gel, electrode overheating leading to pain and/or local skin burns, infections at sites of electrode contact with the skin, local warmth and tingling sensation beneath the electrodes, muscle twitching, medical site reaction and skin breakdown/skin ulcer.

Talk to your doctor if you have any of these side effects or questions.

Caution: Federal law restricts the NovoTTF-100L System to sale by or on the order of a physician. Humanitarian Device. Authorized by Federal Law for use in the treatment of adult patients with unresectable, locally advanced or metastatic, malignant pleural mesothelioma concurrently with pemetrexed and platinum-based chemotherapy. The effectiveness of this device for this use has not been demonstrated.


Please click here to see the Optune Instructions for Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.

Please click here to see the NovoTTF-100L IFU for complete information regarding the device's indications, contraindications, warnings, and precautions.


On this site, patient and healthcare professional videos as well as all images labeled as Optune users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals. All other depictions of patients and caregivers are actor portrayals. Patient images reflect the health status of the patients at the time each photo was taken.

What is Optune approved to treat?

Optune is indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.