Quick facts about Optune

• What Optune is

  Optune is a noninvasive, portable device that is classified as durable medical equipment (DME).

  

  

• How Optune works¹

  Optune provides continuous action against disease progression by delivering Tumor Treating Fields (TTFields) to selectively disrupt mitosis in dividing cancer cells.

  • Watch how TTFields can disrupt cancer cell division. This video shows the mechanism of action of TTFields
• How Optune is used⁴

  Transducer arrays are applied to the shaved scalp and must be changed at least 2 times per week (every 4 days, at most)

  • Arrays should always have good scalp contact
  • Note: Avoid activities that may result in the device or transducer arrays becoming wet. Getting the device wet may cause it damage

  Recommended usage goal for Optune is 18+ hrs/day, which gives patients flexibility to decide which times of day are best for use⁴

  

  Patients can benefit most from wearing Optune for the recommended time

  • In the phase 3 pivotal trial, 75% of patients used Optune 18 or more hours a day during the first 3 months of treatment⁵
    • 50% daily use was the threshold for significant survival benefit over TMZ alone
    • 86% of patients received a survival benefit from Optune, because they used it more than half the time (n=388/450)

  

  Adjusting to Optune

  • This brief video shows Optune users and caregivers providing their perspectives on starting to use Optune

Simple steps to start patients on Optune

Novocure^® has identified a 4-step process that may help your patients with GBM start Optune and achieve their treatment goals.

• Discuss treatment plan with multidisciplinary team, patient, and caregiver
• Submit prescription order form and supporting documentation
• Follow up 2 weeks post Optune initiation, to review integration and skin care
• Manage each patient via monthly follow-ups and review of the Optune Usage Report