Treatment for glioblastoma (GBM)
Intended for US audiences only.

How Optune® works

You might be wondering how a device that creates wave-like electric fields can treat glioblastoma. Here's a look at the science behind Optune.

The video below describes how Optune creates Tumor Treating Fields (TTFields) to slow or stop GBM cells from dividing and may also destroy some of them.

Learn how Tumor Treating Fields work

Get a quick overview of the video in this short slide show

Optune treats where the tumor is

  • GBM tumor cells divide quickly, creating more and more cells that form a mass, or tumor
  • When Optune is turned on, it creates low-intensity, wave-like electric fields call Tumor Treating Fields, or TTFields. These TTFields are delivered by transducer arrays to the location of a GBM tumor
  • TTFields interfere with GBM tumor cell division. This action slows or stops GBM cells from dividing, and may destroy them

How does Optune treat where the GBM tumor is located?

  • Optune has been shown in clinical studies to safely deliver TTFields to the location of a GBM tumor
  • Optune uses 4 adhesive patches, called transducer arrays, to deliver TTFields to the location of a GBM tumor. These transducer arrays are applied to your scalp and are connected to the device and battery

Discover how Optune stops cancer cells from dividing

References:
  1. Optune [Instructions for Use] Novocure 2016.
  2. Optune Patient Information and Operation Manual. Novocure Inc.; 2017.

What is Optune® approved to treat?

Optune is a wearable, portable, FDA-approved device indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

Recurrent GBM

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

Who should not use Optune?

Optune is not for everyone. Talk to your doctor if you have:

Do not use Optune if you are pregnant or are planning to become pregnant. It is not known if Optune is safe or effective during pregnancy.

What should I know before using Optune?

Optune should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure™, the maker of Optune.

What are the possible side effects of Optune?

Most common side effects of Optune when used together with chemotherapy (temozolomide, or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

The most common side effects when using Optune alone were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

Talk to your doctor if you have any of these side effects or questions.


Please click here to see the Optune Instructions for Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.


On this site, patient and healthcare professional videos as well as all images labeled as Optune users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals. All other depictions of patients and caregivers are actor portrayals.

What is Optune approved to treat?

Optune is a wearable, portable, FDA-approved device indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.