Treatment for glioblastoma (GBM)
Intended for US audiences only.

Disease overview

What is the difference between newly diagnosed GBM and recurrent GBM?

When a GBM tumor is first confirmed by your doctor, it’s called newly diagnosed GBM. Even after 1 or 2 years, if your tumor has not come back as visible on your MRI results, it's still called newly diagnosed GBM.

Recurrent GBM is when GBM has come back after a period of time and GBM tumors are visible on your MRI.

Why GBM may return

Surgery, radiation, and/or chemotherapy may have removed or destroyed most GBM tumor cells. But, because of the location of the tumor and the "finger-like tentacles" of a GBM tumor that may spread across the brain, it may be difficult to reach all GBM cells. Some cancerous cells may remain and continue to grow.

References:
  1. Optune [Instructions for Use]. Novocure 2016.
  2. American Brain Tumor Association. Glioblastoma. https://www.abta.org/tumor_types/glioblastoma-gbm/. Accessed May 30, 2018.

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What is Optune® approved to treat?

Optune is a wearable, portable, FDA-approved device indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.

Newly diagnosed GBM

If you have newly diagnosed GBM, Optune is used together with a chemotherapy called temozolomide (TMZ) if:

Recurrent GBM

If your tumor has come back, Optune can be used alone as an alternative to standard medical therapy if:

Who should not use Optune?

Optune is not for everyone. Talk to your doctor if you have:

Do not use Optune if you are pregnant or are planning to become pregnant. It is not known if Optune is safe or effective during pregnancy.

What should I know before using Optune?

Optune should only be used after receiving training from qualified personnel, such as your doctor, a nurse, or other medical staff who have completed a training course given by Novocure™, the maker of Optune.

What are the possible side effects of Optune?

Most common side effects of Optune when used together with chemotherapy (temozolomide, or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

The most common side effects when using Optune alone were scalp irritation (redness and itchiness) and headache. Other side effects were malaise, muscle twitching, fall and skin ulcers.

Talk to your doctor if you have any of these side effects or questions.


Please click here to see the Optune Instructions for Use (IFU) for complete information regarding the device's indications, contraindications, warnings, and precautions.


On this site, patient and healthcare professional videos as well as all images labeled as Optune users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals. All other depictions of patients and caregivers are actor portrayals.

What is Optune approved to treat?

Optune is a wearable, portable, FDA-approved device indicated to treat a type of brain cancer called glioblastoma multiforme (GBM) in adult patients 22 years of age or older.